Metabolism

10 results.

August 5, 2025 ‘Sweet’ discovery reveals how glucose fuels cancer-fighting immune cells

GRAND RAPIDS, Mich. (Aug. 5, 2025) — For cancer- and infection-fighting T cells, glucose offers far more than a simple sugar rush.

A new discovery by…

July 22, 2025 Reducing inflammation may offer new path for treating Peutz-Jehgers syndrome, GI cancers

GRAND RAPIDS, Mich. (July 22, 2025) — Targeting a common inflammatory protein linked to arthritis and allergies may lead to better treatments for gastrointestinal (GI) cancers and…

June 27, 2025 Releasing a molecular ‘brake’ may help immune cells better fight cancer

GRAND RAPIDS, Mich. (June 27, 2025) — Van Andel Institute scientists and collaborators have discovered a potential treatment target that may re-energize dysfunctional or “exhausted” immune…

August 22, 2024 Immune cells have a metabolic backup plan for accessing their anti-cancer playbook

GRAND RAPIDS, Mich. (Aug. 22, 2024) — Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports…

June 3, 2024 Immune cells swap snacks and trade information to do their jobs. Can we help them be more effective?

Dr. Russell Jones spends a lot of time thinking about what our cells eat.

As a scientist who studies the interaction between the immune…

August 8, 2023 Generosity of VAI employees empowers osteoporosis discovery

What started as a question about an odd bone could one day lead to new ways to treat osteoporosis with fewer side effects, thanks to…

July 28, 2023 Alternative cellular ‘fuels’ boost immunity

GRAND RAPIDS, Mich. (July 28, 2023) — A metabolic by-product that is more prevalent during fasting may supercharge immune cells as they fight infection and…

May 11, 2023 Targeting uncontrolled inflammation may hold the key to treating therapy-resistant cancers

GRAND RAPIDS, Mich. (May 11, 2023) — Van Andel Institute scientists have pinpointed how a specific gene mutation triggers an inflammatory cascade that may…